We have used the laser Doppler technique of electrophoretic light scattering to study the electrokinetic and gross conformational manifestations of the binding of divalent cations to DNA in low-salt solutions. By electrokinetic assay, divalent ion affinities to DNA in the 5–500 μM range increase in the order Mn+2
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Rhee et al. (1983) studied this question.
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