A patient with a filarial infection due to Loa loa and renal failure was treated with a modified regimen of diethylcarbamazine while receiving hemodialysis. Infection with Loa loa may be associated with glomerulonephritis due to immunologically mediated injury. Serum immune complexes were elevated in our patient, and a kidney biopsy specimen revealed globally sclerosed glomeruli. As gauged by the clearance of the microfilaremia, the treatment regimen proved safe and effective.
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Katner et al. (1984) studied this question.
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