Key result
APACHE II outperforms SAPS II and SOFA as a predictor of ICU mortality.
Why the study?
The study aimed to compare the predictive accuracy of APACHE II, SAPS II, and SOFA scoring systems for mortality in ICU patients.
Does the APACHE II scoring system predict mortality better than SAPS II and SOFA in ICU patients?
Observational (n=36)
Yes
Does the APACHE II scoring system predict mortality better than SAPS II and SOFA in ICU patients?
p-value: p=<0.001
The APACHE II scoring system is superior to SAPS II and SOFA for predicting mortality in ICU patients.
APACHE II may aid ICU mortality prediction; leaves open superiority to SAPS II/SOFA without prospective validation.
Objective: The comparison of the APACHE II, SAPS II and SOFA scoring systems as predictors of mortality in ICU patients. Study Design: A prospective observational study. Place and Duration of Study: Intensive care unit of Ch. Pervaiz Ellahi Institute of Cardiology and Nishtar Medical University and Hospital, Multan, from May 13, 2018 to September 24, 2018. Methodology: For 36 patients included in study, results for APACHE II, SAPS II and SOFA were calculated with the worst values recorded. At the end of ICU stay, patient outcome was labelled as survivors and non-survivors. Data was analyzed with SPSS v.23. Descriptive data was stated as median (minimum-maximum) or percentages. Pearson Chi square test and non-parametric statistics were applied accordingly. Linear regression analysis was also performed. Cut off value for statistical significance was taken as ≤0.05. Results: Of 36 patients, 22 survived and 14 died after being observed for 12 (2-17) days. On linear regression analysis, all the scoring systems were significantly associated with the mortality rates (p<0.05). However, after adjustment, only the APACHE II was a significant predictor of mortality (p<0.001). APACHE II scoring system calculated highest estimated mortality rates i.e. 19.3%, while SAPS II and SOFA scoring systems estimated 8.6% and 13.5% mortality, respectively. Conclusion: APACHE II scoring system was much superior to SAPS II and SOFA scoring systems as a significant predictor of the mortality among the ICU patients. Keywords: Acute Physiology and Chronic Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), Sequential Organ Failure Assessment (SOFA), Intensive care units (ICU), Mortality. DOI : 10.7176/JMPB/53-03 Publication date :March 31 st 2019
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Raouf et al. (2019) conducted an observational in Critically ill ICU patients (n=36). APACHE II scoring system vs. SAPS II and SOFA scoring systems was evaluated on ICU mortality (p=<0.001). After adjustment, the APACHE II scoring system was the only significant predictor of ICU mortality (p<0.001), proving superior to both SAPS II and SOFA scoring systems.
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