Key result
Sleeve gastrectomy linked to ~29% lower triglycerides and increased HDL in morbidly obese patients.
Why the study?
The effect of sleeve gastrectomy on lipid profiles in morbidly obese patients was not fully characterized.
Does sleeve gastrectomy improve lipid profiles in obese patients?
Cohort (n=163)
No
Does sleeve gastrectomy improve lipid profiles in obese patients?
Sleeve gastrectomy significantly improves triglycerides and HDL cholesterol in morbidly obese patients, though it does not significantly affect total cholesterol or LDL.
Answers are grounded in this paper and cite their sources.
SG-associated TG reduction may inform post-bariatric lipid monitoring; leaves open causality and CV outcome impact in prospective trials.
), undergoing SG, and having complete follow-up records of lipid profiles. Baseline and post-operative lipid profiles, their variation, and the percentage of variation were compared. Results We analyzed data of 163 patients who underwent SG. The mean age was 36.75 ± 10.75 years, the mean BMI was 45.66 ±8.46, and the mean pre-operative TC, LDL, HDL, and TG were 4.67 ± 1.02, 2.55 ± 1.1, 1.14 ± 0.32, and 1.5 ± 1.11, respectively. There was a significant change in the mean level of TG as it was significantly higher pre-operatively compared to its mean level post-operatively. Furthermore, a significant change was observed in HDL. There was a non-significant change in levels of TC and LDL post-operatively. Conclusion SG showed to significantly reduce TG and elevate HDL in morbidly obese patients. On the contrary, TC and LDL were non-significantly affected. Further studies with longer follow-up are warranted to provide more reliable evidence.
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Zaki et al. (2021) conducted a cohort in Morbid obesity (n=163). Sleeve gastrectomy vs. Pre-operative baseline was evaluated on Mean triglyceride level (MD 0.42, p=≤0.05). Sleeve gastrectomy significantly reduced mean triglyceride levels (1.5 vs 1.07 mmol/L) and increased HDL levels in morbidly obese patients.
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