Key result
Thrombus aspiration resolves acute STEMI complicating TEVAR in a patient with protein S deficiency.
Why the study?
Procedure-related thrombotic adverse events during thoracic endovascular therapy in patients with protein S deficiency are very rare and not well documented.
Case Report (n=1)
Highlights the rare risk of procedure-related coronary thrombosis during TEVAR in patients with protein S deficiency despite standard anticoagulation.
May signal periprocedural thrombosis risk in protein S deficiency despite anticoagulation; leaves open optimal management strategies for prospective study.
A 71-year-old woman who had suffered from pulmonary thromboembolism with deep vein thrombosis for 12 years presented the hospital with a huge thoracic aortic aneurysm. During thoracic endovascular therapy, she had a sudden coronary artery occlusion without having organized stenosis or plaque rupture even under the dual antiplatelet treatment and heparinization. She turned out to be having a protein S deficiency. A procedure related thrombotic adverse event in patient with protein S deficiency is very rare, so we report a case with literature review.
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Kim et al. (2014) conducted a case report in Thoracic aortic aneurysm and Protein S deficiency (n=1). Thoracic endovascular aortic repair (TEVAR) was evaluated. A 71-year-old woman with protein S deficiency developed acute ST-elevation myocardial injury due to coronary thrombosis during thoracic endovascular aortic repair, successfully managed with thrombus aspiration.
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