IgE-mediated food intolerance

Many articles reviewing "food allergy" begin by acknowledging that this topic is "controversial" and often "confusing."A recent editorial by Dr. Charles May ~ questioned this continued perception of "confusion" and suggested that a great deal of scientific evidence has been published in this area.One of the earliest descriptions of an adverse reaction to food was recorded by Hippocrates more than 2000 years ago.Since the mid-1800s, an increasing number of articles, largely anecdotal, have been appearing in the medical literature.In 1950, Dr. Mary Loveless 2 published the first series of blinded, placebo-controlled food challenges to evaluate cornstarch hypersensitivity in 25 individuals who purportedly had an allergy to