Meningitis and Skin Reaction after Intravenous Immune Globulin Therapy

Letters15 December 1997Meningitis and Skin Reaction after Intravenous Immune Globulin TherapyE. Peter Gabor, MDE. Peter Gabor, MDUniversity of California, Los Angeles, School of Medicine; Beverly Hills, CA 90212Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-12-199712150-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In his excellent review of high-dose intravenous immune globulin (IVIg) therapy for neurologic diseases, Dalakas [1] states that aseptic meningitis complicating the administration of IVIg responds to analgesics and subsides in 24 to 48 hours and that further diagnostic testing is rarely necessary. In our experience, the symptoms of severe meningeal irritation, high temperature, and vomiting in such cases mandate at least a lumbar puncture for cerebrospinal fluid analysis and possibly other tests. Even if one suspects that meningism could be due to administration of IVIg rather than coincident with it, the possibility of bacterial meningitis should ...References1. Dalakas MC. Intravenous immune globulin therapy for neurologic diseases. Ann Intern Med. 1997; 126:721-30. Google Scholar2. Gabor EP. Intravenous immune globulin. West J Med. 1995; 162:277-8. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of California, Los Angeles, School of Medicine; Beverly Hills, CA 90212 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByIncidence and natural history of intravenous immunoglobulin-induced aseptic meningitis: a retrospective review at a single tertiary care centerRisks associated with the use of intravenous immunoglobulin 1 1This review article reflects the opinions of the authors and not necessarily those of the U.S. Food and Drug Administration.Lichenoid/Interface Cutaneous Eruptions to IVIg with the Primary Infusion May Be Related to the Re-Regulation of Anti-Idiotype Network 15 December 1997Volume 127, Issue 12Page: 1130KeywordsChronic lymphocytic leukemiaDecision makingGlobulinsHospitalizationsLumbar punctureMeningitisMultiple myelomaSkin reactionTemperatureVomiting Issue Published: 15 December 1997 CopyrightCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...