Review highlights Bcl-2 expression as a prognostic indicator in oral squamous cell carcinoma, revealing its contribution to cancer development and treatment resistance.
Currently, oral cancer is one of the most alarming health problems facing mankind. More than 90% of all oral cancers are oral squamous cell carcinoma (OSCC). BCL-2 proteins are one of the most prominent anti-apoptotic proteins expressed in OSCC. They contribute to cancer development and mediate resistance to current anticancer treatments. Various studies have been conducted to evaluate the expression of Bcl-2 in OSCC. This article emphasizes the importance of Bcl-2 expression as a prognostic indicator in OSCC.
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Jayakumar et al. (2017) studied this question.
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