Key result
Complete genome sequencing identifies human echovirus 20 strain linked to severe hand-foot-and-mouth disease.
Why the study?
Human echovirus 20 is often detected in nonpolio enterovirus cases of acute flaccid paralysis, but its complete genome from severe hand-foot-and-mouth disease cases was not determined.
Provides the complete genome sequence of a human echovirus 20 strain associated with severe hand-foot-and-mouth disease.
New E-20 reference genome from HFMD case now available; leaves open its role in severe disease.
Human echovirus 20 (E-20) belongs to the Human enterovirus B (HEV-B) species and is often detected in nonpolio enterovirus cases of acute flaccid paralysis. We determined the complete genome of strain 812/YN/CHN/2010, isolated from a child with severe hand-foot-and-mouth disease in Yunnan, China, in 2010.
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Zhao et al. (2017) studied this question. The complete genome of human echovirus 20 strain 812/YN/CHN/2010 was sequenced from an isolate associated with severe hand-foot-and-mouth disease in a Chinese child.
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