Biosensors based on optofluidic micro-bottle resonators are demonstrated. A self-referenced sensing scheme, differential mode sensing, is proposed and used to substantially suppress environmental noises and reach an ultralow noise equal detection limit of 10 fg/ml (∼0.15 fM) for bovine serum albumin molecules. This sensing scheme has high compatibility with any other microcavity sensors to get lower biosensing limit.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: