Key result
African swine fever reproduction numbers reach ~17 across herds, driven by varying transmission rates.
Why the study?
Mortality data are routinely collected and used for epidemiological purposes, but their utility for inferring transmission parameters of African swine fever virus within herds needed investigation.
Observational (n=9)
Yes
Mortality data can be used to infer transmission parameters for high-mortality diseases like African swine fever virus, though the virus may circulate for weeks before mortality increases substantially.
Answers are grounded in this paper and cite their sources.
Mortality data may support ASF transmission inference; leaves open herd-specific modeling before guiding control.
Mortality data are routinely collected for many livestock and poultry species, and they are often used for epidemiological purposes, including estimating transmission parameters. In this study, we infer transmission rates for African swine fever virus (ASFV), an important transboundary disease of swine, using mortality data collected from nine pig herds in the Russian Federation with confirmed outbreaks of ASFV. Parameters in a stochastic model for the transmission of ASFV within a herd were estimated using approximate Bayesian computation. Estimates for the basic reproduction number varied amongst herds, ranging from 4.4 to 17.3. This was primarily a consequence of differences in transmission rate (range: 0.7-2.2), but also differences in the mean infectious period (range: 4.5-8.3 days). We also found differences amongst herds in the mean latent period (range: 5.8-9.7 days). Furthermore, our results suggest that ASFV could be circulating in a herd for several weeks before a substantial increase in mortality is observed in a herd, limiting the usefulness of mortality data as a means of early detection of an outbreak. However, our results also show that mortality data are a potential source of data from which to infer transmission parameters, at least for diseases which cause high mortality.
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Guinat et al. (2017) conducted an observational in African swine fever virus (ASFV) (n=9). African swine fever virus (ASFV) outbreak was evaluated on Transmission parameters (basic reproduction number, transmission rate, mean infectious period, mean latent period). The basic reproduction number for African swine fever virus varied among herds from 4.4 to 17.3, driven by differences in transmission rates (0.7-2.2) and mean infectious periods (4.5-8.3 days).
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