A 17-year-old girl presented with slow, progressive, painless visual deterioration in the left eye. Fundus examination and fluorescein angiography findings were consistent with combined hamartoma of the retina and retinal pigment epithelium. Spectral domain optical coherence tomography (SD-OCT) displayed a preretinal membrane, retinal disorganization, and thickened retina drawn into folds. Partial posterior vitreous detachment was noted. The higher-resolution scans delineated the transition between the tumor and normal retina. The higher resolution of SD-OCT allows detailed observation of the vitreoretinal interface abnormalities and retinal disorganization present in combined hamartomas of the retina and retinal pigment epithelium and aids in the differential diagnosis and management of pigmented fundus lesions.
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Huot et al. (2009) studied this question.
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