based on a proportionate change in total calcium with protein rather than an absolute change.A slightly improved nomogram would be based on the plasma albumin rather than the total protein and would be derived from the known calcium-albumin associa:ion constant.Such a nomogram can be prepared by any physical chemist and will be included by us in a fo-rthcoming publication.-Weare, etc., R. W.
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Neil R.M. Buist (1974) studied this question.