Clinical outcomes in hypertensive patients undergoing bariartic surgery

Aim: This study aimed to investigate the impact of bariatric surgery (BS) on individuals with hypertension (HT) by assessing changes in clinical and metabolic parameters following BS.Material and Methods: A total of 34 obese individuals undergoing BS were included in the study.Demographic characteristics, including age and gender, were recorded, along with clinical parameters such as body mass index (BMI), glucose levels, blood urea nitrogen (BUN), uric acid, C-reactive protein (CRP), albumin, CRP-to-albumin ratio (CAR), and glycated hemoglobin (HbA1c).Hypertensive patients were further divided into groups based on the use of HT medication.Changes in these parameters were assessed three months post-surgery and compared between groups.Results: No significant differences were observed in age, gender, and most metabolic parameters between groups with and without HT (p>0.05).Although, preoperative BMI was higher in the HT group (p=0.014), the difference was decreased following BS (p=0.059).29.2% of HT patients stopped or reduced doses of antihypertensive medicines.There were no significant differences in glucose, BUN, CRP, CAR, and HbA1c levels between groups.Notably, uric acid levels exhibited a greater reduction in the HT group (mean change of -0.3 vs. -0.1,p=0.026).AKI rates were higher among HT patients with obesity (20% vs 12.5%, p=0.975) but the difference was not significant.Discussion: This study has once again demonstrated that a reduction in blood pressure can be achieved in obese patients with HT following BS.Additionally, it is noteworthy that additional benefits, such as improvements in high uric acid levels in HT patients, can also be observed.These findings reflect the beneficial metabolic consequences of BS.