Key result
Obesity is linked to ~59% higher OSA risk in Black adults with metabolic syndrome.
Why the study?
Identification of risk factors for obstructive sleep apnea is important to enable comprehensive intervention to reduce OSA-related cardiovascular disease among blacks with metabolic syndrome.
Does obesity predict obstructive sleep apnea risk in Black patients with metabolic syndrome?
Cohort (n=1,035)
No
Does obesity predict obstructive sleep apnea risk in Black patients with metabolic syndrome?
Obesity is a strong, independent predictor of obstructive sleep apnea risk among Black patients with metabolic syndrome.
Supports OSA screening considerations in obese Black adults with metabolic syndrome; extends associations but leaves causal effects and practice change open.
INTRODUCTION: Identification of risk factors for obstructive sleep apnea (OSA) is important to enable comprehensive intervention to reduce OSA-related cardiovascular disease (CVD). The metabolic syndrome outcome study (MetSO) provides a unique opportunity to address these factors. This study investigated risk of OSA among blacks with metabolic syndrome. METHODS: ). RESULTS: Of the 1,035 patients screened in the MetSO cohort, 48.9% were at high risk for OSA. Using multivariate-adjusted logistic regression analysis, we observed that obesity was the strongest predictor of OSA risk (OR=1.59, 95%CI=1.24-2.04, p<0.0001). This finding remained significant even after adjustment for known covariates including blood pressure, low-density lipoprotein, high-density lipoprotein, and glucose levels (OR=1.44, 95%CI=1.11-1.86, p<0.001). CONCLUSION: Blacks in the MetSO cohort are at greater OSA risk, relative to the adult population in developed countries. Consistent with previous observations, obesity proved the strongest independent predictor of OSA risk among blacks with metabolic syndrome.
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Rogers et al. (2015) conducted a cohort in Metabolic syndrome (n=1,035). Obesity vs. Non-obese was evaluated on High risk for obstructive sleep apnea (ARES score ≥ 6) (OR 1.59, 95% CI 1.24-2.04, p=<0.0001). Obesity was the strongest predictor of high obstructive sleep apnea risk among black adults with metabolic syndrome (OR 1.59).
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