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March 1, 1996Journal of Thoracic and Cardiovascular SurgeryOpen Access

Long-term results of left ventricular myotomy and myectomy for obstructive hypertrophic cardiomyopathy

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Key result

LV myectomy for HOCM yields ~85% 5-year survival and improves symptoms in most patients.

  • n=158

Why the study?

Long-term outcomes and effectiveness of left ventricular myotomy and myectomy for medically refractory hypertrophic obstructive cardiomyopathy were not well characterized.

Does left ventricular myotomy and myectomy improve survival and symptoms in patients with hypertrophic obstructive cardiomyopathy?

Population

158 patients with hypertrophic obstructive cardiomyopathy, mean age 50.2 years

Comparison

Not applicable, single-arm surgical cohort

Design

Retrospective observational cohort study

Follow-up

Mean 6.1 years

Authors

RRRobert C. RobbinsCardiovascular Institute of the SouthESE B StinsonNorth Idaho College

Discussion

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Implication

Supports myectomy consideration in HOCM; extends retrospective data but leaves open need for prospective confirmation.

Study Design

Type

Observational (n=158)

Structured PICO

Does left ventricular myotomy and myectomy improve survival and symptoms in patients with hypertrophic obstructive cardiomyopathy?

P
Population
158 patients (mean age 50.2 years) with hypertrophic obstructive cardiomyopathy treated by left ventricular myotomy and myectomy, followed for a mean of 6.1 years.
E
Exposure
Left ventricular myotomy and myectomy
O
Outcome
Long-term survival, operative mortality, and symptomatic improvement (New York Heart Association functional class)hard clinical

Left ventricular myotomy and myectomy is a safe and effective long-term treatment for medically refractory hypertrophic obstructive cardiomyopathy, providing significant symptom relief and favorable survival.

Cite This Study

Robbins et al. (1996) conducted an observational in hypertrophic obstructive cardiomyopathy (n=158). Left ventricular myotomy and myectomy was evaluated on 30-day operative mortality. Left ventricular myotomy and myectomy for hypertrophic obstructive cardiomyopathy demonstrated a 3.2% 30-day operative mortality and 85.4% 5-year survival, with symptom improvement in most patients.

synapsesocial.com/papers/6aae4b33ff4a67ca631c25dehttps://doi.org/10.1016/s0022-5223(96)70310-0

Topics

EchocardiographyHypertrophic cardiomyopathy
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-term results of dual-chamber (DDD) pacing in obstructive hypertrophic cardiomyopathy. Evidence for progressive symptomatic and hemodynamic improvement and reduction of left ventricular hypertrophy.1994 · 384 citations
  2. 2Operative treatment in hypertrophic subaortic stenosis. Techniques, and the results of pre and postoperative assessments in 83 patients.1975 · 396 citations