Key result
Coincidental procedures link to ~2% postoperative rupture risk in patients with large aneurysms and hypertension.
Why the study?
The relationship between aortic aneurysmal rupture and coincidental surgical or endoscopic procedures in patients with aortic aneurysmal disease was unclear.
Observational (n=118)
Coincidental surgical or endoscopic procedures in patients with aortic aneurysms may precipitate rupture, especially in those with larger aneurysms and poorly controlled perioperative hypertension.
May warrant caution with coincidental procedures in large aneurysms; leaves open whether BP control mitigates risk.
The clinical course of 76 patients with aortic aneurysmal disease undergoing 107 coincidental surgical procedures was analysed in order to examine the relationship between aortic aneurysmal rupture and coincidental treatment. Additionally the incidence of aneurysmal rupture was assessed following 82 endoscopic procedures in 42 patients with aortic aneurysms. Two patients ruptured an aortic aneurysm after operation, one after colonoscopy (maximal transverse diameter 7 cm) and one after coronary artery bypass grafting (maximal transverse diameter 5.6 cm). The mean maximal transverse diameter of aneurysms in 76 patients was 5.08cm (95% confidence interval 4.7–5.4 cm). Both patients with ruptured aortic aneurysms were outside these confidence limits and were known hypertensives whose perioperative control of hypertension was questionable. The present series of patients is discussed with reference to induction of collagenase activity as a precipitating cause for postoperative rupture of aortic aneurysms, perioperative control of hypertension, transverse aneurysm diameter as a predictor of postoperative rupture and conduct of coincidental procedures in the presence of aneurysmal disease.
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Lalak et al. (1995) conducted an observational in Aortic aneurysms (n=118). Coincidental surgical or endoscopic procedures was evaluated on Aneurysmal rupture. Coincidental surgical or endoscopic procedures in patients with aortic aneurysms resulted in postoperative rupture in 1.7% (2/118) of patients, both with large aneurysms and hypertension.
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