Novel biosynthesis of tellurium nanoparticles and investigation of their activity against common pathogenic bacteria

Objectives: (MRSA), a common blood bacterial pathogen. Methods: using survival assays, colony counting, cytokine assessment and biochemical testing. Results: (15%). The produced TeNPs were tested against MRSA, the bacterium most frequently isolated from blood, and showed a promising action inhibition zone of 24 ± 0.7 mm and an MIC of 50 μg/ml. An animal infection model indicated the promise of TeNPs alone or in combination with standard drugs to combat MRSA in a rat intravenous infection model. Conclusion: TeNPs combined with vancomycin have successive impact to combat bacteremia for further verification of results.