The previously suggested quantitative structure-property relationship was used for predicting properties of aliphatic carboxylic acids. The boiling points, octanol-water partition factors (log P ), and toxicities [log(1/IGC 50 )] were calculated for a series of monocarboxylic, dicarboxylic, and unsaturated monocarboxylic acids. The calculated values are well consistent with the experimental data.
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Golovanov et al. (2006) studied this question.