Aims.We have measured the deuterium fractionation and the CO depletion factor (ratio between expected and observed CO abundance) in a sample of high-mass protostellar candidates, in order to understand whether the earliest evolutionary stages of high-mass stars have chemical characteristics similar to those of low-mass ones. It has been found that low-mass starless cores on the verge of star formation have large values both of the column density ratio and of the CO depletion factor.
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Fontani et al. (2006) studied this question.
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