Key result
Uncontrolled T2D during chemotherapy is linked to lower physical and emotional QoL.
Why the study?
Cancer and diabetes are highly prevalent diseases that greatly influence quality of life, but the impact of comorbid type 2 diabetes on quality of life in cancer patients undergoing chemotherapy was unclear.
Does comorbid type 2 diabetes reduce quality of life in cancer patients undergoing chemotherapy?
Observational (n=200)
Does comorbid type 2 diabetes reduce quality of life in cancer patients undergoing chemotherapy?
Comorbid type 2 diabetes, particularly when poorly controlled or of long duration, negatively impacts the quality of life of cancer patients undergoing chemotherapy.
Answers are grounded in this paper and cite their sources.
Poor glycemic control or longer diabetes duration may worsen QoL domains in cancer patients on chemotherapy; leaves open whether tighter control improves outcomes.
BACKGROUND AND OBJECTIVE: Cancer and diabetes are two highly prevalent diseases worldwide and greatly influence quality of life of those suffering from it. The study aimed to compare quality of life in patients diagnosed with cancer and diabetes with those without diabetes both undergoing chemotherapy and to investigate the factors responsible for the difference between the two groups. METHODS: A convenience sample of 101 participants who had cancer and type 2 diabetes and 99 who had cancer without diabetes were used. RESULTS: Patients with comorbid diabetes were divided based on their diabetes duration and whether they had glycaemic control or not. Diabetic cancer patients without glycaemic control had lower scores in global health status and in physical and emotional functioning compared to diabetic cancer patients with glycaemic control and patients without diabetes (p < .05). After adjusting for demographic characteristics, the differences between the group with diabetes and without glycaemic control and the other two groups regarding global health status were statistically significant (p < .05). Patients with more than a 7-year history of diabetes had a significantly lower emotional functioning than the no diabetes group and lower global health status score than both of the other groups (p < .05). After adjusting for clinical and demographic characteristics, only the difference between the ≥ 7 years diabetes duration group and the no diabetes groups remained significant. CONCLUSION: The presence of diabetes in cancer patients who underwent chemotherapy seems to negatively influence certain domains of quality of life and this may be affected by the duration of diabetes and whether glycaemic control has been achieved or not.
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Lavdaniti et al. (2020) conducted an observational in Cancer undergoing chemotherapy (n=200). Comorbid type 2 diabetes vs. No diabetes was evaluated on Quality of life (global health status, physical and emotional functioning) (p=< .05). Comorbid type 2 diabetes without glycaemic control in cancer patients undergoing chemotherapy was associated with lower global health status and physical and emotional functioning (p < .05).
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