To the Editor: In the September 19, 1968, issue Williams et al. report on seven cases of hyperacute rejection of renal homografts. In at least three of their patients (S.S., M.D. and P.S.) the rejection was evident macroscopically almost immediately upon revascularization of the graft. In all seven kidneys biopsies taken within one hour of transplantation showed polymorphonuclear-leukocyte accumulation in the glomerular and tubular capillaries. Similar histologic appearance has been shown by others1 to signify poor chances of graft survival. From all these it seems that in retransplantations, in which the frequency of hyperacute rejections may be 25 per cent . . .
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Better et al. (1969) studied this question.