Chemotherapy, Testicular Damage and Gynecomastia: An Endocrine “Black Hole”

That young patients with Hodgkin's or other neoplastic diseases should have to be concerned with the effect of therapy on their future fertility is an indication of the immensity of medical progress in recent years. That progress, however, has its "black holes." In the endocrine galaxy, the hormonal function of the testicular tubule and the reason why damage to the tubule may result in gynecomastia stubbornly remain in such a hole, and modern knowledge of the structure, sources, production rates and specific receptors for, and mode of action of, the sex steroids has not enticed them out. Radioimmunoassay of peptide . . .