Commentary to:Dose/dense metronomic chemotherapy with fractioned cisplatin and oral daily etoposide enhances the anti-angiogenic, and anti-tumor activity of bevacizumab in advanced non-small-cell-lung cancer patientsPierpaolo Correale, Cinzia Remondo, Salvatore Francesco Carbone, Veronica Ricci, Cristina Migali, Ignazio Martellucci, Antonella Licchetta, Raffaele Addeo, Luca Volterrani, Giuseppe Gotti, Maria Saveria Rotundo, Pierfrancesco Tassone, Pasquale Sperlongano, Alberto Abbruzzese, Michele Caraglia, Pierosandro Tagliaferri and Guido Francini
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Vitale et al. (2010) studied this question.