Effects Of The Ethanolic Extract Of Rosa Canina On Some Serum Biochemical Factors In Diabetic Adult Male Rats

Medicinal plants play a main role in the management of diabetes mellitus especially in expanding countries where resources are few.Rosa canina L. is a medicinal plant largely used in common folk medicine.The aim of present research is studying effects of Rosa canina extract on amounts of serum biochemical factors in diabetic male rats.In this experiment, 32 male Wistar rats were obtained and randomly divided into four groups (n=8).These groups received normal saline (10mg/kg), RC fruit extract (250 mg/kg) and RC fruit extract (500mg/kg) as oral gavages every day for a period of four weeks, respectively.glucose, cholesterol and triglyceride levels in the serum were determined at the end of the period.The results showed that glucose, cholesterol and triglyceride concentrations were significantly increased in the diabetic group.The levels of glucose, cholesterol and triglyceride significantly decreased in the treatment groups in comparison with the diabetic control group (p<0.05).The changes of glucose,triglyceride in treatment groups showed no significant differences.In contrast the cholesterol differences in groups receiving extract was significant in comparison with the normal saline group.