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December 31, 2004MoleculesOpen Access

Self-organizing Neural Networks for Modeling Robust 3D and 4D QSAR: Application to Dihydrofolate Reductase Inhibitors

Jarosław Polański Andrzej Bąk Rafał Gieleciak Tomasz Magdziarz

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Abstract

We have used SOM and grid 3D and 4D QSAR schemes for modeling the activity of a series of dihydrofolate reductase inhibitors. Careful analysis of the performance and external predictivities proves that this method can provide an efficient inhibition model.

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Cite This Study

Polański et al. (2004) studied this question.

synapsesocial.com/papers/6aaf6a2d11fbe269dcdca25a https://doi.org/10.3390/91201148

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