In control: A cyclization reaction of an allylic β-imidazolinonyl-β-ketoester 1 is carried out in a MnIII-promoted radical cascade. The reaction pathway (5-exo/6-endo or 5-exo/5-exo) can be directed to construct the central cyclopentyl and cyclohexenyl core skeletons (2 and 3) of two classes of oroidin dimers with regiocontrol. An oxidative rearrangement can also be used to convert 2 into 3. PG=protecting group.
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Tan et al. (2006) studied this question.
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