Summary In conclusion, these and similar data illustrate the usefulness of metabolic information in the specific context of the safety assessment of natural food flavours (JECFA 1987). This type of data not only aids the interpretation of toxicity tests, making it possible to devise soundly‐based mathematical models for the assessment of the implications for human health of the consumption of allylbenzenes and other dietary toxicants but also permits the design of more relevant tests. In addition, metabolic data are important in the establishment of testing priorities, by directing limited resources towards compounds most likely to be human health hazards. It must not be overlooked that many natural flavours consist of closely related chemical series and the establishment of structure‐metabolism relationships, as has been achieved with the allylbenzenes, aids in the group assessment of such series without the need for comprehensive testing of individual congeners.
No takes yet. Share an insight, caveat, or question.
Caldwell et al. (1990) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: