Key result
CT-guided FNA biopsy successfully diagnoses metastatic monophasic synovial sarcoma in a lung nodule.
Why the study?
Monophasic synovial sarcoma poses difficult diagnostic challenges on cytology due to its broad differential diagnosis and rarity.
Case Report (n=1)
Highlights the diagnostic utility and challenges of using FNA cytology for identifying monophasic synovial sarcoma.
Supports potential role of CT-guided FNA in rare sarcoma metastases; leaves open validation in larger prospective series.
Synovial sarcomas (SS) are rare soft tissue sarcomas that usually arise near large extremity joints. SS may pose difficult diagnostic challenges on cytology when encountered as a monophasic variant. We report a 27-year-old woman diagnosed with metastatic monophasic synovial sarcoma by a CT-scan guided fine needle aspiration (FNA) biopsy of a left lower lung lobe nodule. We reviewed the literature on the epidemiologic, cytohistological spectrum, immunophenotypic, and the molecular findings and discussed the differential diagnosis for this rare entity.
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Tranesh et al. (2016) conducted a case report in Metastatic monophasic synovial sarcoma (n=1). CT-scan guided fine needle aspiration (FNA) biopsy was evaluated on Diagnosis of metastatic monophasic synovial sarcoma. A 27-year-old woman was successfully diagnosed with metastatic monophasic synovial sarcoma using a CT-scan guided fine needle aspiration biopsy of a left lower lung lobe nodule.
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