Comparison of Central Corneal Thickness and Anterior Chamber Depth Measured Using Three Different Devices

Purpose: To compare measurements of central corneal thickness (CCT) and anterior chamber depth (ACD) obtained using GalileiTM, Pentacam (Oculus, Wetzlar, Germany) and Lenstar (Haag-Streit, Koeniz, Switzerland) and analyze the measurement agreements. Methods: CCT and ACD were measured using GalileiTM, Pentacam and Lenstar in 47 eyes of 25 healthy subjects. The measurements were compared among the 3 devices. Results: The average CCT measurements using GalileiTM, Pentacam and Lenstar were 552.6 ± 29.41 μm, 543.9 ± 30.50 μm and 537.5 ± 30.26 μm, respectively. The measurements significantly correlated with each other (r > 0.9, p 0.9, p < 0.001), but were statistically significantly different (p = 0.034). The CCT 95% limits of agreement (LoA) between GalileiTM and Pentacam, Pentacam and Lenstar and Lenstar and GalileiTM were 31.95 μm, 44.76 μm and 46.57 μm, respectively and 95% ACD LoA were 0.46 mm, 0.32 mm and 0.28 mm, respectively. Conclusions: CCT and ACD measured using the 3 devices were highly correlated with each other but the measurements were statistically different. Therefore, the measurements were not interchangeable and these differences should be considered in clinical use. J Korean Ophthalmol Soc 2015;56(5):694-701