Key result
Intensive BP control in older adults requires careful safety evaluation and frailty management.
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Design
Other
Safety monitoring in older adults supports intensive BP strategies; leaves open optimal targets by frailty status.
In Reply We are grateful to Huang and Tan for their interest in our research.1 Their constructive comments regarding safety evaluation and the management of older populations with frailty offer valuable perspectives for advancing hypertension treatment strategies.
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Guo et al. (2025) studied this question. Intensive blood pressure control in older adults necessitates careful safety evaluation and management of frailty to advance hypertension treatment strategies.
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