Key result
Orthotopic liver transplantation linked to acute apical ballooning syndrome with LVEF drop to 35%.
Why the study?
Orthotopic liver transplantation has complex cardiovascular effects including acute heart failure with apical ballooning syndrome that require recognition for optimal management.
Case Report (n=1)
Highlights the importance of recognizing apical ballooning syndrome as a potential cardiovascular complication following orthotopic liver transplantation, which typically resolves with conservative management.
As the mainstay of therapy for end-stage liver disease (ESLD), orthotopic liver transplantation (OLT) has complex effects on multiple organ systems. We present a representative case of acute heart failure with apical ballooning syndrome following OLT and review its mechanisms. Recognition of this and other potential cardiovascular and hemodynamic complications of OLT are essential to periprocedural anesthesia management. Once an acute phase of the condition is stabilized, conservative treatment and resolution of physical or emotional stressors usually allow for rapid resolution of symptoms, typically recovering systolic ventricular function within one to three weeks.
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Badwan et al. (2023) conducted a case report in Apical ballooning syndrome (Takotsubo cardiomyopathy) (n=1). Orthotopic liver transplantation was evaluated on Development of apical ballooning syndrome. A 52-year-old woman developed acute heart failure with apical ballooning syndrome, characterized by an LVEF drop from 65% to 35%, six days after orthotopic liver transplantation.
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