Answers are grounded in this paper and cite their sources.
Substitution of the new diamine antibiotic SQ109 for ethambutol in a mouse model of chronic tuberculosis (TB) improved efficacy of combination drug therapy with first-line TB drugs rifampin and isoniazid, with or without pyrazinamide: at 8 weeks, lung bacteria were 1.5 log10 lower in SQ109-containing regimens.
No takes yet. Share an insight, caveat, or question.
Nikonenko et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: