Bacterial Etiology And Their Antibiograms in Community Acquired Urinary Tract Infections with Special Consideration on Sterile Pyuria

Urinary tract infections are caused by heterogenous etiological agents and high proportions of samples are without significant growth. Antibiotic resistance issue constitutes a major public health problem. A retrospective study was conducted from a period of January,2021 to May 2023 in which a total of 419 mid urine samples were collected. The ages were ranged from 4 months to more than 65 years. Adults were 348 (83.1%) and children were 71 (16.9%). Females were 358 (85.5%) and Males were 61 (14.5%). From 419 samples 193 (46.3%) were normal (pus cells < 5/HPF), while 225 (53.7%) were abnormal (Pus cells >5/HPF). Among 225 abnormal samples, 100 (44.5%) showed no growth, while 125 (54.5%) yielded significant growth. Among males 21/ 123 (17%) of the samples showed growth compared to 102 /123 (83%) in females. Among the isolated pathogens, E. coli was the predominant (71%) followed by Staphylococcus aureus (14%), Streptococcus spp. (6%), Proteus spp. (5%), Pseudomonas aeruginosa (3%) and Klebsiella pneumoniae (1%). High percentages of total UTIs and E. coli were found among age group 20-30 years. The highest percenatge of resistant was against doxycycline (87.61%) followed by trimethorprim (86.66%), cephalothin (86.06%), ceftriaxone (60.97%), amoxyclav (57.02%), ciprofloxacin (41.22%) while the lowest resistant was against Amikacin (25.2%) followed by Gentamicin (34.14%), nitrofurantoin (37.39%).