The objective of the current research was to investigate the possible association between Periodontal Disease indices and risk of development Acute Hematopoietic Cancer (Acute Myeloid and Acute Lymphoblastic Leukemia) in a representative Greek adult sample. 174 individuals with Acute Myeloid and Acute Lymphoblastic Leukemia-cases and 174 matched healthy individuals- controls underwent an oral and dental clinical examination and completed a questionnaire. The periodontal condition for cases and controls included Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL) and Gingival Index (GI). Chi-square test and logistic regression models were carried out to assess the possible association. The logistic regression model showed that CAL (p= 0.054) (OR= 2.467, 95% CI= 1.177-2.231), and GI (p= 0.043) (OR = 3.352, 95% CI= 1.285-4.745), were marginally significantly associated with an increased risk of developing Acute Hematopoietic Cancer.
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Chrysanthakopoulos et al. (2022) studied this question.
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