The Ethical Aspects of Germline Gene Editing

Globally, Germline Gene Editing is considered as a cheap, efficient and accurate innovative tool.Genome editing techniques in general have contributed to the therapy of challenging human diseases such as various types of cancer, neurodegenerative diseases, Duchenne muscular dystrophy, AIDS, Sickle cell anemia, Hemophilia, Autism spectrum disorder etc.But due to the various scientific achievements there is the need for regulations and ethical guidelines.Various ethical issues emerge which need to be addressed.In this review, the ethical aspects related to the new innovation are dealt with.Germline Gene Editing has associated advantages as well as disadvantages.It is observed that the advantages outweigh the disadvantages.Nevertheless, Germline Gene Editing is not considered practical enough and there is a need for stringent guidelines on the global level.The ethical guidelines taken by involvement of states, judiciary and public engagements will be necessary in future to decide whether somatic or germline gene editing is permissible.Gene editing in human somatic cells is conducted for therapeutic purposes but basic and clinical research is required.Germline Gene editing may pose health risks for the present and future generations.Therefore, requires in-depth research, debates and clarifications of regulations and guidelines.Thus, it is also imperative and important to understand the scope and future approach pertaining to this new innovative technique.