When to ConsiderIt is recommended that antidepressants should be chosen primarily based on their relative efficacy, their tolerability and safety, comorbid conditions, cost, patient preference, and prior medication history.16 This holds true for augmentation treatments as well.Among many augmentation options, lithium stands out because of its efficacy in preventing relapses and recurrences of mood episodes.3 In addition, lithium augmentation has been found to be superior to
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Ercis et al. (2023) studied this question.
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