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Several oximes and oximeethers of hydroxylated benzaldehydes and acetophenones were investigated for their antioxidative potential and compared with further standards. Radical scavenging activity was determined using a photometric assay based on the colored radical 2, 2-diphenyl-1-picrylhydrazyl and a superoxide anion quenching assay using luminol amplified chemiluminescence. The activity against lipid autoxidation was measured by accelerated autoxidation of soybean oil, evening primrose oil, and squalene. All tested catecholoximes show good to excellent antioxidative properties. 3, 4-Dihydroxybenzaldoxime shows the best overall performance and is a very powerful radical scavenger and lipid antioxidant.
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Ley et al. (2002) studied this question.
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