Self-aggregates of Hydrophobic Polysaccharide Derivatives

Hydrophobic polysaccharide derivatives bearing palmitoyl or cholesterol moieties form self aggregates in an aqueous solution. The critical concentrations to give the polymer aggregates depended on the degree of substitution of the hydrophobic moiety. Cholesterol-bearing pullulan showed a stronger binding for hydrophobic guest molecules and higher colloidal stability compared with the corresponding palmitoyl-bearing one.