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xtracranial internal carotid artery dissection can lead to occlusion of the artery and hence cause an ischemic stroke.It is the underlying stroke mechanism in approximately 2.5% of all strokes.It is the second leading cause of stroke in patients younger than 45 years of age.Anticoagulants or antiplatelets may prevent arterial thrombosis in extracranial internal carotid artery dissection, but these benefits may be offset by increased bleeding.
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Lyrer et al. (2004) studied this question.
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