, 630-634] show the superior plasticity in hydrates of the pharmaceutical drugs, pregabalin and gabapetin, compared with their anhydrous forms. The water in the structure is believed to act as a lubricating agent in the packing of hydrates, thus facilitating slippage of molecules in the plastic bending of the crystals under external mechanical stress.
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C. Malla Reddy (2019) studied this question.
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