Key result
Elevated AFP of 6101 ng/mL linked to late-stage HCC in a hepatitis C patient.
Why the study?
The correlation between alpha-fetoprotein levels and hepatocellular carcinoma development in a high-prevalence region was investigated.
Case Report (n=1)
No
The study highlights a correlation between elevated alpha-fetoprotein levels and the development of hepatocellular carcinoma in a Pakistani demographic.
Does not support practice change from one case; leaves open validation of AFP thresholds in Pakistani hepatitis C cohorts.
Hepatocellular carcinoma prevalence rate is higher in Pakistan due to HCV mortality rate, consumption of Alchol, and regular smoking, higher level of AFP progression normal liver cells into fatty liver cells, after inflammation it convert into HCC.In this study, we find the correlation between AFP and hepatocellular carcinoma.AFP involve in development of liver cancer, LFT's test elevation and HCV also cause of cancer.
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A 2022 study conducted a case report in Hepatocellular carcinoma (n=1). Alpha Fetoprotein (AFP) elevation was evaluated on Diagnosis of Hepatocellular carcinoma. In a 56-year-old male with hepatitis C, an elevated alpha-fetoprotein level of 6101 ng/ml correlated with a diagnosis of late-stage hepatocellular carcinoma.
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