Herein is described the development and use of a novel bis(dialkylamino)sulfur difluoride reagent to effect the stereoselective conversion of a benzylic alcohol into a benzylic fluoride. A new method for the synthesis of 1H-pyrazolo[3,4-d]pyrimidin-4-amines is reported. Additionally, a practical method for the addition of a hindered alkoxide to an epoxide is demonstrated.
No takes yet. Share an insight, caveat, or question.
Bio et al. (2008) studied this question.