Key result
Roux-en-Y gastric bypass yields greater weight loss than sleeve gastrectomy at five years.
Why the study?
Controversies exist regarding which bariatric surgery technique, Roux-en-Y gastric bypass or sleeve gastrectomy, achieves better long-term weight loss.
Does Roux-en-Y gastric bypass improve weight loss compared to sleeve gastrectomy in patients aged 18 to 65 years with obesity?
Systematic Review
Does Roux-en-Y gastric bypass improve weight loss compared to sleeve gastrectomy in patients aged 18 to 65 years with obesity?
Roux-en-Y gastric bypass appears to provide greater long-term weight loss than sleeve gastrectomy at 5 years or more.
RYGB was associated with greater 5-year weight loss and fewer reflux issues than SG; extends observational data but leaves open need for randomized trials.
INTRODUCTION: Bariatric surgery is currently the gold standard treatment for obesity. The two most accomplished surgeries are the Roux-en-Y gastric bypass and the sleeve gastrectomy, and controversies exist in which is better. OBJECTIVE: To compare the two techniques in relation to weight loss with at least five years of follow-up. METHODS: Search in Medline, PubMed, Embase, SciElo, Lilacs, Cochrane databases from 2001 (beginning of vertical gastrectomy) until 2018, using the following headings: "sleeve" or "sleeve gastrectomy" combined with "gastric bypass" or "Roux-en-Y gastric bypass", "weight loss" and "clinical trial". Criteria for inclusion of articles were patients aged between 18 and 65 years; clinical trial; comparison between the two techniques; minimum five-year follow-up; outcome with weight loss assessment. RESULTS: The initial search identified 1940 articles, of which 185 publications were identified as clinical trials. One hundred and forty-one were excluded, 67 because they did not compare the two techniques, 57 not addressed weight loss and 17 were repeated articles. Thirty-four studies were retrieved for a more detailed analysis; 36 studies were excluded due to a follow-up of less than five years, and another compared the mini-gastric bypass. In total, seven studies were included in the systematic review, but there was no significant difference in three of them. CONCLUSION: The gastric bypass had a greater weight loss than the vertical gastrectomy in all the evaluated studies.
No takes yet. Share an insight, caveat, or question.
Barros et al. (2019) conducted a systematic review in Obesity. Roux-en-Y gastric bypass vs. Sleeve gastrectomy was evaluated on Weight loss. Roux-en-Y gastric bypass resulted in greater weight loss than sleeve gastrectomy across 7 clinical trials with at least 5 years of follow-up, though 3 studies showed no significant difference.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: