Notes on a Case of Indigenous Infection withP. Falciparum

In their preliminary note on this case, Glynn and Matthews (1920) have furnished an account of the fi.ndings at the post-mortem examination and also details of the history.For convenience we may recapitulate here briefly the main facts. Histor-y.The patient was a girl, aged 18, who had never been out of the British Isles; she was born in Liverpool and had once been South-to London in 1914, from July to September, during which period she spent three weeks at Littlehampton; she had lived for the last ten years in the same house in Liverpool.She died on October i2th, 1920, after a period of illness which commenced (on her return from a holiday in a northern health resort) with 'feverishness and flushed appearance' on October 1st, followed on October 2nd and 3rd and several other occasions by vomiting.On October 8th she was overcome with faintness in the street, and had to be helped home.Her condition r-apidly became worse with severe headache, thirst, photophobia, delirium, paresis of legs, anuria, and fi.nally coma.The temperature on October 1 Ith, the day before death, was 100° F., and on October 12th, just before death, ~02° F. Further investigation elicited the facts that she had always been pale, had suffered from headaches since Christmas, 1919, and that she had vomited on September 29th, 1920.The following notes on the post-mortem examination are quoted from the paper mentioned above : -'The post-mortem examination was made twenty hours after death.Blood: anaemic.Brain : apparently normal, no meningitis.Lungs: a moderate amount of oedema and muco-purulent bronchitis.Heart: weight, 8 oz., normal, no fatty degeneration.Mouth: healthy, no trace of pyorrhoea.Oesophagus, stomach and intestines opened from end to end-normal, no evidence of blood.Some of the lumbar lymphatic glands slightly enlarged, and red like haemolymph glands.L£r•er: wei~ht, 3 lbs., slightly browner than normal, no haemosiderin reaction.