Provisional Study of Kuwait Adult Hematology Reference Range

Introduction: Hematology reference range provides valuable information for the correct interpretation of results for proper diagnosis and treatment.Previous studies have shown that hematology reference range may vary in people of various continents.Method: From 95,501 subjects a normal 500 females and 500 male Kuwaiti fulfilling the criteria of normal individuals were chosen in this study from October 2012 to March 2013 with no medical follow up required until March 2016 study.The Hb concentration; HCT ratio; RBC count, MCV; MCH; MCHC; red cell distribution width (RDW); WBC count; absolute neutrophil count (ANC); lymphocyte, monocyte, eosinophil, and basophil counts; PLT count; platelet mean volume (PMV) were evaluated and compared with adult UK hematology reference range (AUK-HRR) which our analyzer standardized according to it. Results:The obtained hematology reference range in this study considered the adult provisional Kuwaiti hematology reference range (APK-HRR).The APK-HRR categorized patients with slight microcytic hypochromic anemia and a slightly increased RBC, WBC and platelet count within the normal Kuwaiti population.Conclusion: A significant difference was observed between APK-HRR and AUK-HRR when the slight microcytic hypochromic picture and high RBC count in AUK-HRR found within the normal range of APK-HRR.The slightly high WBC and platelets count in APK-HRR excluded any infection or underlying disease in Kuwaiti population.The regional factors including ethnicity, genetics, and environment could affect the complete blood count.Standardizing local or regional hematology reference range should be mandatory.