Preparation of Alkylmagnesium Reagents from Alkenes through Hydroboration and Boron–Magnesium Exchange

Tolerant: Alkylmagnesium reagents can be synthesized from alkenes through a sequence of hydroboration and subsequent boron–magnesium exchange using a method that tolerates different functional groups (see scheme). The resulting alkylmagnesium reagents can be used in carbon–carbon bond forming reactions, such as alkylation reactions or transition-metal-catalyzed cross-coupling reactions.