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December 19, 2023Frontiers in ImmunologyOpen Access

Unlocking the potential of dimethyl fumarate: enhancing oncolytic HSV-1 efficacy for wider cancer applications

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Authors

AAAkram AlwithenaniBrigham and Women's HospitalZTZaid TahaUniversity of OttawaMTMax ThomsonOttawa Hospital

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Cite This Study

Alwithenani et al. (2023) studied this question.

synapsesocial.com/papers/6ab08653f954e110ea852f48https://doi.org/10.3389/fimmu.2023.1332929
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma2005 · 59 citations
  2. 2DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner2015 · 173 citations
  3. 3Dimethyl fumarate induces necroptosis in colon cancer cells through <scp>GSH</scp> depletion/<scp>ROS</scp> increase/<scp>MAPKs</scp> activation pathway2015 · 145 citations
  4. 4Utilization of Dimethyl Fumarate and Related Molecules for Treatment of Multiple Sclerosis, Cancer, and Other Diseases2016 · 86 citations