Key result
Intramuscular vitamin B12 linked to a ~3-fold serum increase and resolution of nutritional optic neuropathy.
Why the study?
Bariatric procedures may cause gastrointestinal malabsorption leading to nutritional optic neuropathy, but clinical awareness and management strategies are limited.
Does intramuscular vitamin B12 supplementation resolve nutritional optic neuropathy following bariatric surgery?
Case Report (n=1)
Does intramuscular vitamin B12 supplementation resolve nutritional optic neuropathy following bariatric surgery?
Vitamin B12 supplementation can rapidly resolve nutritional optic neuropathy, a potential complication of bariatric surgery.
May support short-course IM B12 in post-bariatric optic neuropathy; hypothesis-generating case report requiring prospective confirmation.
Bariatric procedures, associated with gastrointestinal malabsorption of vitamins and microelements, may constitute a risk factor for nutritional optic neuropathy (NON). We present a case of a 34-year-old female patient who developed bilateral NON after sleeve gastrectomy. Despite postoperative ophthalmological supervision, 10 months after the procedure the woman presented with a bilateral decrease in visual acuity down to 0.8, bilateral visual field loss and abnormal visual evoked potential recordings. Laboratory abnormalities included decreased serum concentration of vitamin B12 (161 pg/ml). Treatment was based on intramuscular injections of vitamin B12 (1000 units per day). After 1 week of the treatment, we observed more than a three-fold increase in the serum concentration of vitamin B12 and resolution of the bilateral symptoms of NON. The incidence of NON is likely to increase due to the growing number of these bariatric procedures performed worldwide. Therefore, all persons subjected to such surgery should receive long-term ophthalmological follow-up and supplementation with vitamins and microelements.
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Sawicka-Pierko et al. (2014) conducted a case report in Nutritional optic neuropathy (n=1). Intramuscular injections of vitamin B12 was evaluated on Resolution of symptoms and serum concentration of vitamin B12. Intramuscular injections of vitamin B12 (1000 units/day) for 1 week led to a more than three-fold increase in serum vitamin B12 and resolution of bilateral nutritional optic neuropathy symptoms.
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