Monsel's solution applied to biopsy sites causes tissue necrosis that can persist for two weeks and impede reepithelialization. Granulation tissue in the healing phase contains iron pigment residue from the agent. The pigment encrusts upon collagen and is present in siderophages for up to three months. Occasionally pigment or necrotic residues incite a foreign body giant cell reaction. Awareness is recommended in order to avoid confusion. The agent's potential effect upon the basic disease is discussed.
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Davis et al. (1984) studied this question.
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